University of Minnesota researchers are reporting a major advance in the field of embryonic stem cell research that undercuts the anti-abortion movement’s — and Gov. Tim Pawlenty’s — chief argument against state funding for the research.
The researchers used human embryonic stem cells (hESCs) to create immune cells to fight cancer and found a 100-percent success rate at eliminating cancerous tumors in 13 trials. The researchers also used human umbilical cord blood cells, the type of cells anti-abortion activists say are equal to hESCs, and only five trials of 13 saw the successful elimination of cancerous tumors.
“This is the first demonstration of anti-cancer activity in a living organism by cells derived from human embryonic stem cells,” said study leader Dan Kaufman, an associate professor of medicine and associate director of the University’s Stem Cell Institute, in a statement. “The superior performance by cells with an hESC lineage points to a crucial role for hESCs in developing new cell-based cancer therapies.”
The Minnesota Legislature passed a bill in 2008 that would have allowed state funding to be used for embryonic stem cells research,but it was met with Pawlenty’s veto pen. He did so at the behest of anti-abortion group Minnesota Citizens Concerned for Life.
“The biotech industry wants you to pay for its ruinous research,” says MCCL’s anti-embryonic stem cell pamphlets, “but not even a lab mouse has ever benefited from embryonic stem cell research.”
All thirteen of the successful University of Minnesota trials eliminated cancerous tumors in lab mice.
Because of Pawlenty’s veto last year, legislators have taken a different approach to getting state support for hESC research. Instead of a bill to allow state funding for the research, Rep. Phyllis Kahn, DFL-Minneapolis, has put forward a bill that requires fertility clinics to inform patients about the options for discarded embryos — including stem cell research.
But Republican House members want to eliminate research on viable embryos. Their bill, the Minnesota Hope Act, would limit research in Minnesota to “naturally dead” embryos. Reps. Matt Dean of Dellwood, Laura Brod of New Prague, Steve Gottwalt of St. Cloud, Joe Ward (DFL) of Brainerd, Tom Emmer of Delano, Tara Mack of Apple Valley, Jim Abeler of Anoka and Mary Ellen Otremba (DFL) of Long Prairie.
Neither bill passed out of committee this session.













8 Comments »
Comment posted May 6, 2009 @ 9:30 am
I’m pro-life, and I can say pro-lifers do not equate umbilical stem cells with embryonic stem cells. Umbilical stem cells are not pluripotent, as are embryonic.
Pro-lifers DO say induced pluripotent stem cells (iPS) stem cells are equivalent to embryonic stem cells. iPS stem cells are made by reprogramming an adult cell into an embryonic-like state. Even Oprah’s famous “Dr Oz” said the stem cell debate is dead and the future of stem cell research lies in iPS cells — mainly because they, unlike embryonic stem cells, are a genetic match to the patient. He also said embryonic stem cells have a tendency to form tumors.
Comment posted May 6, 2009 @ 4:11 pm
Jim, that’s interesting. Could you provide a source/link to what “Dr Oz” said about induced pluripotent stem cells? I sincerely hope the debate is done if iPS truly works better.
Comment posted May 6, 2009 @ 4:49 pm
Godspeed to all the researchers and scientists. Don’t let the religious zealots hold the progress for humanity back. they will be first in line when the therapies are ready and will forget their indignation.
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Comment posted May 7, 2009 @ 12:26 pm
Advanced Cell Technology (ACTC) is a stem cell company that has shown they can create stem cells without harming the embryo (Aug 2006).
They take a single cell from the embryo and can create stem cells. The procedure is the same performed in IV clinics to check for gene abnormalities.
The debate is over!!! Look at actc
Comment posted May 8, 2009 @ 3:08 pm
Above poster is correct. The company by the name Advanced Cell Technology, can in fact generate human embryonic stem cells without harming the embryo. This is not IPS, where an adult stem cell is merely induced into an embryonic-like state. Advanced Cell Technology actually derives real human embryonic like stem cells without destruction or harm to the embryo. It’s amazing work that has gotten lots of recognition from the science community. The controversy is in fact over, as long as politicians can come to grips with reality.
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Comment posted May 29, 2009 @ 11:07 am
Joshua
Comment posted May 6, 2009 @ 4:11 pm
Jim, that’s interesting. Could you provide a source/link to what “Dr Oz” said about induced pluripotent stem cells? I sincerely hope the debate is done if iPS truly works better.
Dr. Oz to Oprah and Michael J Fox: “The stem cell debate is dead.”
http://www.youtube.com/watch?v=lDFJOzu9SyM
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